三十年代末四十年代初，米高梅影片公司拍摄了几部连集片，其中的《吉尔达医生》很受欢迎，莱昂纳尔·巴里摩尔共参加了《妙手疗心》等十五集的演出，扮演要角吉莱斯皮医生。1938年他因关节炎加上腿部受伤，导致瘫痪，不宜行动，但他仍然积极地从事电影表演工作，在《空谷芳草》等影片中，他扮演的角色是坐在轮椅上的。莱昂纳尔·巴里摩尔写过一本小说《广东酒先生》，一本回忆录《我们巴里摩尔》(1951年出版)。他能绘画、蚀刻，也善作曲，为了纪念他的弟弟约翰·巴里摩尔，他谱写过带有诗意的抒情小曲《追思曲》，1942年曾由费城交响乐队公开演奏。

家庭成员：

父亲：莫里斯·巴里摩尔（电影演员）

母亲：乔治亚娜·德鲁 Georgiana Drew（电影演员）

弟弟：约翰·巴里摩尔John Barrymore（电影演员）

妹妹：埃塞尔·巴里摩尔ethel barrymore（电影演员）

婚姻状况：

第二任妻子：Irene Fenwick（演员）（1923年6月14日—1936年12月24日）

第一任妻子：Doris Rankin（演员） （1904年6月19日—1922年12月21日）

巴里摩尔家族

Our Mr. Sun (1956) (TV) (voice) (uncredited) (unconfirmed) .... Father Time

Lone Star (1952) .... Andrew Jackson

Bannerline (1951) .... Hugo Trimble

Right Cross (1950) .... Sean O'Malley

Malaya (1949) .... John Manchester

Down to the Sea in Ships (1949) .... Capt. Bering Joy

Key Largo (1948) .... James Temple

Dark Delusion (1947) .... Dr. Leonard Gillespie ... aka "Cynthia's Secret" - UK, USA (working title)

Duel in the Sun (1946) .... Sen. Jackson McCanles ... aka "King Vidor's Duel in the Sun" - UK (complete title), USA (complete title)

The Secret Heart (1946) .... Dr. Rossiger

It's a Wonderful Life (1946) .... Henry F. Potter ... aka "Frank Capra's It's a Wonderful Life" - USA (complete title)

Three Wise Fools (1946) .... Dr. Richard Gaunght

The Valley of Decision (1945) .... Pat Rafferty

Between Two Women (1945) .... Dr. Leonard B. Gillespie

Dragon Seed (1944) (uncredited) (voice) .... Narrator

Since You Went Away (1944) .... Clergyman

3 Men in White (1944) .... Dr. Leonard B. Gillespie

A Guy Named Joe (1943) .... The General

The Last Will and Testament of Tom Smith (1943) .... Gramps

Dr. Gillespie's Criminal Case (1943) .... Dr. Leonard B. Gillespie

Tennessee Johnson (1942) .... Thaddeus Stevens

Dr. Gillespie's New Assistant (1942) .... Dr. Leonard Gillespie

Calling Dr. Gillespie (1942) .... Dr. Leonard Gillespie

Dr. Kildare's Victory (1942) .... Dr. Leonard Gillespie

Lady Be Good (1941) .... Judge Murdock

Dr. Kildare's Wedding Day (1941) .... Dr. Leonard Gillespie

The People vs. Dr. Kildare (1941) .... Dr. Leonard Gillespie

The Bad Man (1941) .... Uncle Henry Jones

The Penalty (1941) .... 'Grandpop' Logan

Dr. Kildare's Crisis (1940) .... Dr. Leonard Gillespie

Dr. Kildare Goes Home (1940) .... Dr. Leonard Gillespie

Dr. Kildare's Strange Case (1940) .... Dr. Leonard Gillespie

The Stars Look Down (1939) (voice) (uncredited) .... Narrator

The Secret of Dr. Kildare (1939) .... Dr. Leonard Barry Gillespie

On Borrowed Time (1939) .... Julian Northrup (Gramps)

Calling Dr. Kildare (1939) .... Dr. Leonard Gillespie

Let Freedom Ring (1939) .... Thomas 'Tom' Logan - an old farmer

Young Dr. Kildare (1938) .... Dr. Gillespie

You Can't Take It with You (1938) .... Grandpa Martin Vanderhof

Test Pilot (1938) .... Howard B. Drake

A Yank at Oxford (1938) .... Dan Sheridan

Navy Blue and Gold (1937) .... Capt. 'Skinny' Dawes

Saratoga (1937) .... Grandpa Clayton

Captains Courageous (1937) .... Captain Disko Troop ... aka "Rudyard Kipling's Captains Courageous" - USA (complete title)

A Family Affair (1937) .... Judge James K. Hardy

Camille (1936) .... Monsieur Duval

The Gorgeous Hussy (1936) .... Andrew Jackson

The Devil-Doll (1936) .... Paul Lavond

The Road to Glory (1936) .... Papa La Roche/Pvt. Morin

The Voice of Bugle Ann (1936) .... Springfield 'Spring' Davis

Ah, Wilderness! (1935) .... Nat Miller

The Return of Peter Grimm (1935) .... Peter Grimm

Public Hero #1 (1935) .... Dr. Josiah Glass

Mark of the Vampire (1935) .... Professor Zelen

The Little Colonel (1935) .... Col. Lloyd

The Personal History, Adventures, Experience, & Observation of David Copperfield the Younger (1935) .... Dan Peggotty ... aka "David Copperfield" - USA (short title)

Treasure Island (1934) .... Billy Bones

The Girl from Missouri (1934) .... T.R. Paige ... aka "Born to Be Kissed" - USA (alternative title)

Carolina (1934) .... Bob Connelly

This Side of Heaven (1934) .... Martin Turner

Should Ladies Behave (1933) .... Augustus Merrick

Christopher Bean (1933) .... Dr. Milton Haggett

Night Flight (1933) .... Robineau

One Man's Journey (1933) .... Dr. Eli Watt

Dinner at Eight (1933) .... Oliver Jordan

The Stranger's Return (1933) .... Grandpa Storr

Looking Forward (1933) .... Tim Benton

Sweepings (1933) .... Daniel Pardway

Rasputin and the Empress (1932) .... Grigori Rasputin

The Washington Masquerade (1932) .... Jefferson Keane

Grand Hotel (1932) .... Otto Kringelein

Arsène Lupin (1932) .... Det. Guerchard

Broken Lullaby (1932) .... Dr. H. Holderlin

Mata Hari (1931) .... Gen. Serge Shubin

The Yellow Ticket (1931) .... Baron Igor Andreeff

Guilty Hands (1931) .... Richard Grant

A Free Soul (1931) .... Stephen Ashe

The Mysterious Island (1929) .... Count Andre Dakkar

The River Woman (1928) .... Bill Lefty

West of Zanzibar (1928) .... Mr. Crane

Alias Jimmy Valentine (1928) .... Doyle

Road House (1928) .... Henry Grayson

The Lion and the Mouse (1928) .... John Ryder

Drums of Love (1928) .... Duke Cathos de Alvia ... aka "Sentimental Tommy" - USA (alternative title)

Sadie Thompson (1928) .... Alfred Davidson

The Thirteenth Hour (1927) .... Prof. Leroy

Body and Soul (1927) .... Dr. Leyden

Women Love Diamonds (1927) .... Hugo Harlan

The Show (1927) .... The Greek

The Temptress (1926) .... Canterac

The Bells (1926) .... Mathias

The Lucky Lady (1926) .... Count Ferranzo

Paris at Midnight (1926) .... Vautrin

Wife Tamers (1926) .... Mr. Barry

The Barrier (1926) .... Stark Bennett

Brooding Eyes (1926) .... Slim Jim Carey

Ben-Hur: A Tale of the Christ (1925) (uncredited) .... Crowd extra in chariot race ... aka "Ben-Hur" - USA (short title)

Die Frau mit dem schlechten Ruf (1925) .... Allan Merrick

The Splendid Road (1925) .... Dan Clehollis

Fifty-Fifty (1925) .... Frederick Harmon

The Wrongdoers (1925) .... Daniel Abbott

Children of the Whirlwind (1925) .... Joe Ellison

The Girl Who Wouldn't Work (1925) .... Gordon Kent

A Man of Iron (1925) .... Philip Durban

I Am the Man (1924) .... James McQuade

Meddling Women (1924) .... Edwin Ainsworth/John Wells

Decameron Nights (1924) .... Saladin

America (1924) .... Capt. Walter Butler

Wedding Women (1924)

The Eternal City (1923) .... Baron Bonelli

Unseeing Eyes (1923) .... Conrad Dean

Enemies of Women (1923) .... Prince Lubimoff

The Face in the Fog (1922) .... Boston Blackie Dawson

Boomerang Bill (1922) .... Boomerang Bill

Jim the Penman (1921) .... Jaames Ralston

The Great Adventure (1921) .... Priam Farll

The Devil's Garden (1920) .... William Dale

The Master Mind (1920) .... Henry Allen ... aka "Sinners Three" - USA (alternative title)

The Copperhead (1920) .... Milt Shanks

National Red Cross Pageant (1917) .... Undetermined role and episode

The Millionaire's Double (1917) .... Bide Bennington

His Father's Son (1917) .... J. Dabney Barro

The End of the Tour (1917) .... Bron Bennett

The Brand of Cowardice (1916) .... Cyril Hamilton

The Upheaval (1916) .... Jim Gordon

The Quitter (1916/I) .... Happy Jack Lewis

Dorian's Divorce (1916) .... Richard Dorian

A Yellow Streak (1915) .... Barry Dale

Dora Thorne (1915) .... Lord Earle

The Flaming Sword (1915) .... Steve

The Romance of Elaine (1915) .... Marcus Del Mar/Mr. X

The Curious Conduct of Judge Legarde (1915) .... Judge Randolph Legarde ... aka "The Valley of Night" - USA (reissue title)

A Modern Magdalen (1915) .... Lindsay

Wildfire (1915) .... John Keefe

Under the Gaslight (1914) .... William Byke

The Exploits of Elaine (1914) .... Undetermined Role

The Seats of the Mighty (1914) .... Monsieur Doltaire

The Span of Life (1914) .... Richard Blunt

The Woman in Black (1914/I) .... Robert Crane

The Power of the Press (1914) .... Steve Carson

Men and Women (1914) .... Stephen Rodman/Robert Stevens

Woman Against Woman (1914)

Brute Force (1914) ... aka "Primitive Man" - USA (short title)... aka "The Primitive Man" - USA

Strongheart (1914) .... Billy Saunders

Judith of Bethulia (1914) .... Extra ... aka "Her Condoned Sin" - International (English title) (reissue title)

The Massacre (1914)

Her Father's Silent Partner (1914)

Classmates (1914) .... Dumble

The House of Discord (1913)

The Battle at Elderbush Gulch (1913)

All for Science (1913) .... In Detective Agency

So Runs the Way (1913) (unconfirmed) .... Undetermined Role

The Stolen Treaty (1913) .... The Japanese Diplomat

The Strong Man's Burden (1913) .... John

The Crook and the Girl (1913) .... The Nephew

The Work Habit (1913) .... The Father

The Suffragette Minstrels (1913) (unconfirmed)

An Indian's Loyalty (1913) .... The Cattle Buyer

I Was Meant for You (1913) .... Lavina's Father

Under the Shadow of the Law (1913) .... Charles Darnton, the Employer

The Vengeance of Galora (1913) (unconfirmed)

The Mirror (1913) .... Daisy's Father

The Enemy's Baby (1913) .... Ben Brown

A Gamble with Death (1913) .... Jim Benton, the Bartender

In Diplomatic Circles (1913) .... The Japanese Ambassador

Almost a Wild Man (1913) .... In Audience

The Switch Tower (1913) .... First Counterfeiter

Death's Marathon (1913) .... The Financial Backer

The Well (1913) .... The Farmer

Red Hicks Defies the World (1913) .... The Referee

A Timely Interception (1913) .... The Farmer's Brother

The Ranchero's Revenge (1913) .... The Ranchero

Just Gold (1913) .... First Brother

The Yaqui Cur (1913) .... The Easterner

The House of Darkness (1913) .... The Doctor

The Wanderer (1913/II) .... The Male Lover

The Lady and the Mouse (1913) .... The Young Woman's Father

A Misunderstood Boy (1913) .... The Father

The Little Tease (1913) .... In Bar

The Perfidy of Mary (1913) .... Mary's Father

The Sheriff's Baby (1913) .... Third Bandit

Fate (1913/I) .... Father, Loving Family

Near to Earth (1913) .... Gato

The Unwelcome Guest (1913) .... At Auction ... aka "An Unwelcome Guest" - USA (alternative title)

A Girl's Stratagem (1913)

The Wrong Bottle (1913) .... The Father

Love in an Apartment Hotel (1913) .... In Hotel Lobby

A Chance Deception (1913) .... A Policeman

Oil and Water (1913) .... In First Audience/In Second Audience/Visitor

The Tender Hearted Boy (1913)

An Adventure in the Autumn Woods (1913) .... The Father

The Telephone Girl and the Lady (1913) .... The Desk Sergeant

Three Friends (1913) .... Second Friend

The God Within (1912) .... The Woman of the Camp's Lover

A Cry for Help (1912) .... The Bum

The Burglar's Dilemma (1912) .... The Householder

My Hero (1912)

The New York Hat (1912) .... Preacher Bolton (minister)

Brutality (1912) .... At Wedding

The Informer (1912) .... Union Soldier

My Baby (1912) .... At Table

Gold and Glitter (1912) .... The Lover

Heredity (1912) .... Woodsman

The Musketeers of Pig Alley (1912) .... The Musician's Friend

The Painted Lady (1912) .... At Ice Cream Festival

The One She Loved (1912) .... The Neighbor

The Chief's Blanket (1912) .... The Young Man

So Near, Yet So Far (1912) .... In Club

Friends (1912) .... Grizzley Fallon (Dandy Jack's friend)

Home Folks (1912)

The Miser's Heart (1911) .... Jules, the Thief

The Battle (1911) .... Wagon Driver

Fighting Blood (1911)

The Paris Hat (1908)